10 civilians actually managed to make it out of the Bustan al-Basha District through the passage, despite the heavy fire, the first civilians to get out of the area in some time.
There have been unconfirmed reports of rebels setting up checkpoints to stop people leaving and of shooting at the "humanitarian corridors" designated by the government to let people out.
Iran's veterans' affairs office said that more than 1,000 combatants sent from Iran to fight in support of President Bashar al-Assad had been killed in the conflict.
As they advanced on Tuesday, the army accused the rebels of using the more than 250,000 civilians trapped in the east as "human shields".
The offensive has killed at least 143 civilians in the city's east, among them 19 children, and more than 375 in all of Aleppo province.
On Tuesday, the Syrian army issued a statement accusing rebels of holding civilians as "hostages".
For the past four years, Aleppo has been divided between the government-controlled west and rebel-held east, which has been sealed off from the outside world since the army surrounded it in mid-July.
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A week into the latest round of fighting for the city, the regime controls around a third of the district, the Observatory said.
Both Damascus and its ally Moscow have strongly denied any illegal military use of the chemical.
The renewed bloodshed has stoked global concern, though there has been little sign so far of a plan to halt it.
He urged the worldwide community to "stop averting its gaze" from the "terrible reality" of the conflict. Konashenkov said that United Nations assurances should also include free access to humanitarian caravans for the population, as well as the evacuation of wounded and sick people.
On Wednesday, UN Under-Secretary-General for Humanitarian Affairs and Emergency Relief Coordinator Stephen O'Brien said that between 200,000 and 300,000 civilians were still held by terrorists in the eastern neighborhoods of Aleppo.
The truce deal would have allowed the opposition administration in east Aleppo to remain in place, at least temporarily, in return for extremist fighters leaving. But the government rejected it, insisting the state had to retake control as any alternative would "reward terrorists". This news story is related to Print/167286-Aleppo-civilians-try-to-flee-as-Syria-army-advances/ - breaking news, latest news, pakistan ne.