2-month-old Maxwell Keener and 20-month-old Adelyn Keener were last in Payne County, OK.
An Amber Alert that was issued for two children has been cancelled.
Officials said the children were believed to be in immediate danger because Lewis has been accused of using meth while in their presence.
The children are said to be in good condition. She is 2 feet, 6 inches tall and weighs about 30 pounds.
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Authorities are looking for a mother and two children who were last seen in Payne County on Thursday morning.
Adelyn Keener has hazel eyes and blonde hair.
She is driving a 2002 silver Infinity I-35 with Oklahoma tag 107FCR. The direction of travel is unknown. They were believed to have been taken by their mother, 31-year-old Sarah Jane Lewis.
If you see the vehicle or Lewis, call the Delaware County Sheriff's Office at 918-253-4531 or 911.