The 44-year-old Colon was working on a flawless game for the Texas Rangers before walking Carlos Correa on a 3-1 pitch to start the eighth.
If Colon is able to hold the Astros hitless the rest of the way, he'll become the first Ranger to throw a no-hitter since Kenny Rogers tossed a flawless game against the California Angels on July 28, 1994.
A leadoff walk to Carlos Correa and a Josh Reddick double ended the bid by Colon, who would have become the oldest pitcher to throw a no-hitter.
The right-hander has thrown 76 pitches and will take a bid for a flawless game into the seventh inning at Minute Maid Park.
Opposing fans in Houston gave Colon a standing ovation, and he clapped his bare hand softly against the outside of his glove. Colon is at 83 pitches.
Pravin Togadia quits as President after three decades
Recently, Togadia after a miraculous escape in a road accident near Surat, voiced suspicion that it was an attempt to kill him. Togadia has lately been at loggerheads with senior BJP leaders and had claimed that there was threat to his life.